Thursday 4 June 2015

Study finds that muscle fibrosis inhibition causes increases in utrophin levels and revertant myofibers in Duchenne Muscular Dystrophy

Study finds that muscle fibrosis inhibition causes increases in utrophin levels and revertant myofibers in Duchenne Muscular Dystrophy: "In a recent study published in Oncotarget, researchers found an inverse correlation between the level of muscle fibrosis, utrophin and the number of revertant myofibers in Duchenne Muscular Dystrophy (DMD).

Results from this study reveal common links between the fibrotic and utrophin-synthesis pathways and offer new insights into the regulation of utrophin synthesis in Duchenne Muscular Dystrophy."



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